Set in a run-down psychiatric ward, The Game and Tyler are shown as patients of the ward, with The Game being wheeled to his room by a nurse and Tyler locked up in his room.
While Lil Wayne contributes to the track, he does not appear in the music video.
In January, The Game was ordered to pay his cousin over a fight at a family funeral.
The fight was about the funeral costs at a service for his sister in 2010.
Days later, The Game was injured on the set of his music video after a stunt of him smashing a guitar on the ground backfired.
Watch the music video for The Game's 'Martians Vs Goblins' below: