The American nu-disco band will release 'Shady Love' in January. The song will feature rapper Azealia Banks.
Addressing fans on Facebook, they revealed: "We hope you are having a great Christmas and looking forward to a very exciting 2012 filled with new music, shows, and surprises. One such surprise is coming your way sooner than you thought!
"We've spent 2011 making an album that we're really proud of and can't wait to share with you. Because you've been such good boys and girls, we'll be kicking off 2012 with a sneak peek of a brand new song to whet your appetite for what's to come."
Singer Ana Matronic first announced in September that the group were working on a fourth studio album - a follow-up to 2010's Night Work.
Scissor Sisters' 'Shady Love' will receive its first play on Radio 1 on January 2 between 10am and 1pm.
Watch the video for Scissor Sisters track 'Fire with Fire' below: