The rapper advances two places on this week's midweek chart to claim the top spot, pushing Coldplay's 'Paradise' down to number two.
Olly Murs is at three with 'Dance With Me Tonight', Labrinth's 'Earthquake' is at four and Avicii completes the top five with 'Levels'.
Rizzle Kicks leap four places to six with 'Mama Do The Hump', while Taio Cruz is the highest new entry at eight with 'Troublemaker'.
JLS storm into the chart with 'Do You Feel What I Feel?' landing at 13, while Jessie J's new single 'Domino' launches 17 places to 17.
Over on the album chart, Adele's 21 is on course to reclaim the number one position during its 50th week of release.
Bruno Mars remains at two with Doo-Wops & Hooligans, while Ed Sheeran slips to three with +.
> View the current singles top 100 here
Watch the music video for Flo Rida's 'Good Feeling' below: