The rapper's latest effort pulled 'Paradise' by Coldplay off the top spot after rising from last Sunday's three in its eighth week of release.
Taio Cruz scores today's highest new entry at three with 'Trouble Maker', while 'Levels' by Avicii - which is sampled on Flo Rida's chart-topping track - also improves its position this week, advancing to four from its previous finish at 12.
The climbers countine elsewhere in the Top 10, as 'Mama Do The Hump' by Rizzle Kicks heads from ten to five and Jessie J's 'Domino' leaps a hefty 26 places to eight. Last week's runner-up 'Dance With Me Tonight' by Olly Murs settles between them at six.
Rihanna and Calvin Harris drop four to nine with 'We Found Love', the trio of Lloyd, Andre 300 and Lil Wayne climb three to ten with 'Dedication To My Ex (Miss That)' and LMFAO's 'Sexy And I Know It' is booted back out of the top-sellers after a brief return last week, slipping two to 11.
Big losses are posted later in the rankings by Ed Sheeran's 'Lego House', down six to 13, the 2011 Christmas number one 'Wherever You Are' by the Military Wives choir, down from four to 14, and 'Cannonball' by X Factor winners Little Mix, which crashes nine to 15.
JLS, meanwhile, record their lowest-charting debut to date with 'Do You Feel What I Feel' at 16 and fellow X Factor alum Olly Murs appears again at 19 with 'Heart Skips A Beat', stumbling four to 19.
The top 20 is completed by new mother Beyoncé, whose 'Love On Top' record sneaks back to the upper digits from last week's 22.
The Top 10 in full:
1. (3) Flo Rida: 'Good Feeling'
2. (1) Coldplay: 'Paradise'
3. (-) Taio Cruz: 'Trouble Maker'
4. (12) Avicii: 'Levels'
5. (10) Rizzle Kicks: 'Mama Do The Hump'
6. (2) Olly Murs: 'Dance With Me Tonight'
7. (8) Labrinth ft. Tinie Tempah: 'Earthquake'
8. (34) Jessie J: 'Domino'
9. (5) Rihanna ft. Calvin Harris: 'We Found Love'
10. (13) Lloyd ft. Andre 3000 & Lil Wayne: 'Dedciation To My Ex (Miss That)'
Source: Official Charts Company
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