The pair will play a few of their hits at the event, which will be hosted by Radio 1's Greg James at London's Savoy Hotel on January 12.
The performances were confirmed via the music event's official Twitter account, which stated: "Proud to announce that @emelisande and @edsheeran be performing at Thursday's nominations launch event."
The show will also include the announcement of this year's Brit Award nominees ahead of the official ceremony at London's O2 Arena next month.
Sandé was recently announced as the recipient of this year's Brits Critics' Choice Award, beating Maverick Sabre and Michael Kiwanuka to the accolade.
Jessie J will be in attendance for Thursday night's show to present Sandé with her award, after winning the prestigious gong herself in 2011.
The Brit Awards 2012 will be aired live on February 21 on ITV1.
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Watch the music video for Emeli Sandé's recent single 'Daddy' below: