The rapper has been added to the ceremony's lineup, which will include performances from the Foo Fighters and country singer Jason Aldean.
Kelly Clarkson, Taylor Swift and Bruno Mars will also perform at the event after each picking up a number of nominations each for their respective releases over the past year.
MInaj is also nominated for four awards at the show including 'Best New Artist' and 'Best Rap Album' for her debut LP Pink Friday.
The 54th annual Grammy Awards will air live from the Staples Centre in Los Angeles on February 12 from 8pm (ET/PT) on CBS.
Minaj will release her second studio album Pink Friday: Roman Reloaded in the UK on February 13 and the US on February 14.
> Nicki Minaj promises more alter egos for new album 'Roman Reloaded'
Listen to Nicki Minaj's new song 'Stupid Hoe' below: