The singer's 2011 international hit 'Someone Like You' was the most popular karaoke hit last year after it made up 14% of the total amount of songs performed on website Lucky Voice.
The star's cover version of 'Make You Feel My Love' came in second place with 10%, while 'Rolling In The Deep' polled at number seven.
Lucky Voice managing director Nick Thistleton said: "Adele has got one of the greatest voices in contemporary pop so it's no surprise our customers want to test themselves against the best and pick her songs in such overwhelming numbers."
The X Factor finalists' version of David Bowie's 'Heroes' is at number three, while One Direction's debut single 'What Makes You Beautiful' trails at four.
Jessie J's 'Price Tag' finished up at number five at the end of the year, with the results being collected from three million songs sung by over 100,000 users.
> Adele beats Lady GaGa as most listened-to artist on Last.fm in 2011
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Watch the music video for Adele's 'Someone Like You' below: