The band confirmed that most of the material has already been written and that the follow-up to What Did You Expect From The Vaccines? will "definitely" be released later this year.
Frontman Justin Young told NME: "It's mostly written and we're going into the studio in Belgium in March to start recording so it'll definitely be out this year, without a doubt.
"We've definitely got six songs written that we all want to be on the record, but there's tonnes of other new songs and we're actually going into the studio out in Australia to work on ideas. I think we're in a good place with it and it's quite exciting."
The group also revealed that they will be working with producer Ethan Johns on the project, who has previously collaborated with the Kings of Leon.
Young added: "The reason we wanted to work with Ethan is not because he's a hit manufacturer, but he's a real songs man.
"If you listen to the records he's made, there's a real warmth there, all his albums are simple, but really well crafted and it feels like they really breathe.
"Our first record is quite linear, so it'd be nice to have something that breathes a bit more and with a bit more warmth and maturity, but that still sounds like us."
The Vaccines are up for 'Best Breakthrough Act' at next month's Brit Awards in London and have described the recognition as "surreal".
Watch the music video for The Vaccines' latest single 'Tiger Blood' below: