The music festival will announce its headline acts and a majority of the bill at 7.15pm on March 12, with tickets for the three-day event to go on sale at the same time.
Reading and Leeds will remain in their usual slot in the UK festivals calendar, taking place across the weekend of August 24 to August 26.
Last year's event saw headline performances from Muse, My Chemical Romance, Pulp and The Strokes, while other sets came from 30 Seconds To Mars, Friendly Fires and The Vaccines.
Muse used the headline slot to perform their classic album Origin of Symmetry in full, in celebration of its tenth anniversary.
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Watch Muse perform 'Knights Of Cydonia' live at Reading 2011 below: