The Maybach is estimated at a value of between $100,000 (£63,000) and $150,000 (£95,000).
A portion of the proceeds from the auction, which will be held in New York City on March 8, will be donated to the Save the Children organisation.
The Maybach can be viewed prior to the auction at 450 Park Avenue in New York City from Monday to Saturday at 10am-6pm and on Sunday at 12pm-6pm.
Earlier this month, Jay-Z headlined two concerts at New York's Carnegie Hall for a fundraiser for both United Way of New York City and his own non-profit organisation, the Shawn Carter Scholarship Foundation.
Jay-Z released the first images of his and Beyoncé's daughter Blue Ivy on February 10, which were posted on blogging website Tumblr.
Watch the music video for 'Otis' below: