The band will play seven dates across the country in May, following their induction into the US Rock and Roll Hall of Fame in April.
The tour will begin at Nottingham's Capital FM Arena on May 19 and finish at London's O2 Arena on May 31.
Current members include singer Axl Rose, keyboard players Dizzy Reed and Chris Pitman, bassist Tommy Stinson, rhythm guitarist Richard Fortus, drummer Frank Ferrer plus lead guitarists Ron Thal and DJ Ashba.
The original members of Guns N' Roses, which include Slash and Izzy Stradlin, will reunite for their enrolment into the Rock and Rock Hall of Fame in Ohio on April 14.
Tickets for Guns N' Roses' 2012 UK tour go on sale from 9am on March 3.
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Guns N' Roses' 2012 UK arena tour dates are as follows:
- May 19 - Nottingham, Capital FM Arena
- May 20 - Liverpool, Echo Arena
- May 23 - Newcastle, Metro Radio Arena
- May 25 - Glasgow, SECC
- May 26 - Birmingham, LG Arena
- May 29 - Manchester, Manchester Evening News Arena
- May 31 - London, O2 Arena