The 'Rockin' in the Free World' singer will give an address and be interviewed at BookExpo America on June 6.
Young's speech will feature an overview of his upcoming memoir Waging Heavy Peace.
The musician's autobiography will reveal details of his childhood, early musical career and rise to prominence as one of rock's most enduring stars.
BookExpo America is held at the Jacob Javits Centre in New York City.
Young announced this week that his new album Americana - which features his legendary backing band Crazy Horse – will be released in June.
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Watch Neil Young perform 'Heart of Gold' below: