The London-born rapper has freestyled over the US superstar's new cut 'Climax', which will appear on his new mixtape Wretchercise.
Wretch 32 posted the track online yesterday (March 23) with the message: "New mixtape called #wretchercise 1st 3style (on the house) usher 'climax' enjoy ahh yeaaa."
The star is yet to confirm the release of the new collection of material or whether he will be sampling any further songs for the project.
Wretch 32 recently featured on an All-Star remix of Labrinth's 'Earthquake', which also included cameos from Tinie Tempah, Kano and Busta Rhymes.
Meanwhile, 'Climax' will serve as the lead single for Usher's upcoming album, which is due out later this year.
> Usher's new album: First listen
Listen to Wretch 32's remix of Usher's 'Climax' below: