Adele has been nominated in 18 categories including 'Top Artist', where she will compete against Lady GaGa, Rihanna, Katy Perry and Lil Wayne. 'Rolling in the Deep' is recognised in seven categories alone.
LMFAO follow with recognition in 17 categories. Rihanna, who was nominated for 18 different awards last year, is a finalist in 13 categories this year.
Lady GaGa and Lil Wayne each receive the nod in 10 unique categories, while Bad Meets Evil, Big Sean, Foster The People, Scotty McCreery and Wiz Khalifa are recognised in the 'Top New Artist' category.
Recent winners of the 'Top New Artist' trophy include Justin Bieber in 2011 and Ke$ha in 2010.
The awards are based on Billboard chart positionings from March 1, 2011 to February 29, 2012.
The Billboard Music Awards will be broadcast live from the MGM Grand in Las Vegas on Sunday, May 20 at 8/7c on ABC.
Watch Adele perform 'Someone Like You' live below: