She was the most outspoken member of girl group TLC and her records away from Tionne 'T-Boz' Watkins and Rozonda 'Chilli' Thomas hinted at a whole other career of unrealised potential.
To mark her passing and celebrate her work, we round up six of her best videos with and without her group.
'Never Be The Same Again' (with Melanie C)
'The Block Party'
> TLC 'planning comeback concert'
> TLC are not 'replacing' Left-Eye
What is your favourite musical moment from Lisa 'Left Eye' Lopes? Let us know in the comments box below.