The pair will play 13 cities across North America this summer, starting in Montreal on July 14 and finishing in Miami on August 31.
The show will include a collection of hits from each of their respective back catalogues and a potential duet of recent collaboration 'Mouth2Mouth'.
The North American tour announcement is expected to be the first round of dates for a complete world tour, which will be Lopez's first ever global jaunt with her material.
All tickets go on sale from May 4, with passes for the Montreal date becoming available a day later on May 5.
The dates for Enrique Iglesias and Jennifer Lopez's joint US tour are as follows:
July 14 - Montreal Bell Centre
July 17 - Toronto Air Canada Centre
July 20 - Newark Prudential Centre
July 25 - Boston TD Garden
July 28 - Washington DC Verizon Centre
August 3 - Chicago United Centre
August 8 - San Jose HP Pavilion
August 11 - Anaheim Honda Centre
August 16 - Los Angeles Staples Centre
August 25 - Dallas American Airlines CTR
August 26 - Houston TX, Toyota Centre
August 29 - Atlanta Philips Arena
August 31 - Miami American Airlines Arena
Watch the music video for Jennifer Lopez's latest single 'Dance Again' below: