The 'A Team' singer was due to continue opening shows for the Northern Irish band until their Texas show on May 18, but has had to return to England for "personal reasons".
"Sorry to announce that I have to miss the last 4 days of the Snow Patrol tour, have to get back to England, but I'll be back in June and Sept," Sheeran wrote on Twitter.
"Hope everyone understands, lots of love. So sorry to cancel, have to get home for personal reasons."
Sheeran recently confirmed that he will release his debut album + in the US on June 12. The star also revealed plans to return to America on his own headline tour to support the record next month.
Watch the music video for Ed Sheeran's 'The A Team' below: