The Oasis singer-songwriter's new rock band are added to a bill that includes One Direction, Usher and Jack White among others.
Noel Gallagher's High Flying Birds will play at the Roundhouse on Wednesday, September 12.
Scottish R&B singer Emeli Sandé joined the gig's wide-ranging lineup last Friday (May 18).
Gallagher has also been confirmed as a headliner at the Jersey Live festival on September 2 and will also play at T in the Park and the Isle of Wight festivals this summer.
He will embark upon an arena tour in September supported by Blur guitarist Graham Coxon and The Kooks.
Tickets for Gallagher's Roundhouse show are available via a free-to-enter ballot on the official iTunes Festival website.
Watch Noel Gallagher's High Flying Birds' video for 'AKA... What a Life' below: