The event kicked off with performances by Daughtry and Trace Adkins on the National Mall, until thunderstorms rolled through the District of Columbia.
Sinise, who hosted the event, brought the show to a close early and advised those in attendance to seek shelter as weather conditions worsened.
The National Memorial Day Concert airs annually on PBS stations across the US on the night before the holiday.
Natalie Cole, Colin Powell, Joe Mantegna and American Idol's Jessica Sanchez all took part in this year's National Memorial Day Concert.
Sinise has been very active in honouring veterans and campaigning for military charities in recent years, including holding a series of benefit shows for wounded soldiers.
Watch Daughtry perform 'Home' at the National Memorial Day Concert below: