The girl group have signed a joint deal with toymaker Vivid and music merchandiser Bravado to release a range of products including dolls, puzzles, accessories and games this November.
"We are thrilled to be working with Little Mix and look forward to delivering a full product range to fans and collectors in time for Christmas," said Neil Bandtock, Vivid UK managing director.
David Boyne, Bravado's UK MD, added: "We are delighted to bring together Britain's most exciting new girl band and Britain's leading toymaker Vivid, I am confident that between us we will be delivering some of the most exciting products the market will be seeing this year."
Meanwhile, Jane Kennedy, director of licensing at Modest Management who look after Little Mix, said: "We are delighted to be working with Vivid as the fashion doll and accessories partner for Little Mix.
"The girls love fashion and so it's fitting that this passion is being extended into their doll line."
Little Mix are expected to release their first single proper this summer following their X Factor winner's single 'Cannonball' back in December.
Watch Little Mix perform 'Don't Let Go' on The X Factor below: