The Soundgarden singer said the British songstress would be the ideal candidate to record the Skyfall theme tune as she doesn't rely on computerised vocals.
"Adele would be the perfect choice, I can't think of a better one," Cornell told MTV.
"She's phenomenal and it's nice, in a day and age where so many vocals are fixed by computers, that the biggest album of last year was somebody who sings for real.
"I would hate to see music become more mechanistic and less human, so her success has been great."
Adele has been heavily linked to the next Bond soundtrack for some time and hinted that she was recording a new song during an interview with Jonathan Ross last September.
"I'm going back in the studio in November, fingers crossed," she stated. "Well, this is actually a theme, what I've got to do. Wow, that's really giving something away."
Cornell recorded 'You Know My Name' as the Bond theme for 2006's Casino Royale.
Watch the official music video for 'You Know My Name' below: