The band will release 'Survival' as their new single this evening (June 27) at 8pm GMT after premiering the song on Zane Lowe's Radio 1 show in the UK from 7pm.
The new cut will serve as the official song of the London 2012 Olympic Games and will be played throughout all sports sessions during the entire competition.
Muse appeared at the official London 2012 press conference earlier today (June 27) to launch the Rock The Games music programme, which 'Survival' will lead.
"It's a huge honour to have the track chosen as such a major part of the London 2012 Olympic Games," said frontman Matt Bellamy.
"I wrote it with the Games in mind as it expresses a sense of conviction and determination to win."
Muse will release their sixth studio album The 2nd Law on September 17, with a world tour to follow from October.
Watch the trailer for Muse's The 2nd Law below: