The third single from her MDNA collection will be released on August 5 through Interscope.
The track was confirmed as her next single following 'Give Me All Your Luvin'' and 'Girl Gone Wild' last month.
It is co-produced by Madonna and French electronic DJ Martin Solveig.
Madonna filmed the accompanying music video for the single last month in Florence, Italy.
The singer was recently slammed by Deadmau5, who told her to have some "dignity" while on tour.
Listen to 'Turn Up the Radio' below: