The hip-hop star recently opened up about his sexuality by revealing that his first love was a man.
Beyoncé and Ocean previously worked together for the former's 4 album, with both co-writing 'I Miss You' for the collection.
Supporting Ocean's decision to reveal his sexuality, the former Destiny's Child star posted an image of the Odd Future singer with tag lines such as "Be Honest" and "Be Brave" on her official website.
Meanwhile, Busta Rhymes has praised Ocean for his decision, saying: "Whatever that man does in his personal space is that man's choice and that man's business.
"I am an extremely huge fan of Frank Ocean. His music is impeccable to me, and as far as I'm concerned, I respect the dude completely."
Frank Ocean will release his debut album Channel Orange on July 17.
Watch the music video for Frank Ocean's 'Thinkin Bout You' below: