The Florence Welch-fronted act move up to the top spot in Ireland with 'Spectrum', while will.i.am's 'This Is Love' slips to two.
Flo Rida is at three with 'Whistle', Maroon 5 is at four with 'Payphone' and Chris Brown is at five with 'Don't Wake Me Up'.
Stooshe advance to number seven with 'Black Heart', David Guetta is up to 18 with 'I Can Only Imagine' and Far East Movement and Cover Drive climb to 21 with 'Turn Up the Love'.
Elsewhere, BoB and Taylor Swift are at 32 with 'Both of Us', Lady Antebellum's 'Need You Now' is at 36 and Misha B's debut single 'Home Run' lands at number 46.
This week's Irish Top 10 is as follows:
1. (5) Florence + the Machine: 'Spectrum (Say My Name)'
2. (1) will.i.am ft. Eva Simons: 'This Is Love'
3. (2) Flo Rida: 'Whistle'
4. (3) Maroon 5 featuring Wiz Khalifa: 'Payphone'
5. (4) Chris Brown: 'Don't Wake Me Up'
6. (8) Coldplay and Rihanna: 'Princess of China'
7. (11) Stooshe: 'Black Heart'
8. (6) Katy Perry: 'Wide Awake'
9. (7) fun. featuring Janelle Monaé: 'We Are Young'
10. (9) Cheryl: 'Call My Name'
Watch the music video for Florence + the Machine's 'Spectrum' below: