The Calvin Harris-remixed track was able to hold off the challenge from former number one 'Payphone' by Maroon 5 by over 7,000 copies.
Chris Brown rises one place to three with his number one single 'Don't Wake Me Up', while will.i.am drops one to four with 'This is Love'. Stooshe complete the top five with 'Black Heart'.
Flo Rida stays at six with 'Whistle', while Rudimental enjoy an eighth week inside the Top 10 with non-mover 'Feel the Love' at seven.
Coldplay and Rihanna are a non-mover with 'Princess of China' at eight, while Nicki Minaj rises one spot to nine with 'Pound the Alarm'. Katy Perry drops one place to ten with 'Wide Awake'.
Former X Factor star Misha B scored this week's highest new entry with her debut single 'Home Run', which lands at 11.
Angel's second single 'Wonderful' also enters at 20, while 'Both of Us', B.o.B's duet with Taylor Swift, is a new entry at 22.
Lady Antebellum continue to see a resurgence as their 2010 hit 'Need You Now' climbs a further three spots to 15, a new peak.
Far East Movement and Cover Drive's collaboration 'Turn Up the Love' climbs 41 places to this week's 28, while Kylie Minogue just misses out on the main chart, by rising 105 places to 42 with 'Timebomb'.
Watch the video for Florence + the Machine's 'Spectrum' below:
Source: Official Charts Company
> This week's albums chart