The Scottish DJ will team up with Florence + the Machine for new cut 'Sweet Nothings', which is expected to premiere in the coming months.
The star revealed the news during an interview with Q magazine, where he also confessed that two artists turned down the opportunity to record his international hit 'We Found Love'.
"It was going to be the third single off my new album and I needed a vocalist, so it was like, 'Anyone want to sing on this?'" Harris recalled. "Then someone said, I do, and it was Rihanna.
"Two other people could have released it, though."
Asked if he hangs around with the Bajan singer now they have worked together on two tracks, the producer joked: "She's tried. She's like, yeah come on and hang out in my dressing room.
"I'm like, 'Arrghh'. I mean what do I say to Rihanna? There's nothing! She's great, she's well friendly, she's nice, I see that. But… I can't. I'm from Dumfries, man!"
Calvin Harris's new single 'We'll Be Coming Back', which is a collaboration with Example, will be released in the UK on July 29.
Watch the music video for Calvin Harris and Example's 'We'll Be Coming Back' below: