The singer will feature on Kendrick Lamar's new single 'Partynauseous', which will be released on September 6. It has been lifted from his major label debut good kid, m.A.A.d city.
"I am so excited to announce that a record I've been working on has now become a collaboration with @KendrickLamar for HIS ALBUM," GaGa tweeted.
"@kendricklamar and I are dropping the record SEPT 6. Its called "PARTYNAUSEOUS," she added.
GaGa recently posted a picture of herself and Lamar in the recording studio while she was working on her third studio album ARTPOP.
The star has previously confirmed that her next collection is likely to be out in spring 2013, but revealed that a formal announcement will be made in September.
Watch the music video for Kendrick Lamar's latest track 'Swimming Pools (Drank)' below: