The rapper was revealed as the highest-earning hip-hop star in the past year, despite not having released an album in over ten years.
The majority of Dre's $110 million (£69m) income is from his Beats by Dr Dre headphones line, which HTC bought a 51% stake ($300 million) in last year.
Diddy lands at number two with earnings of $45m (£28m), thanks mostly to his stake in Diageo's Ciroc vodka.
Jay-Z, who topped the 2011 list, pulled in over half of his $38m (£24m) from business ventures, including ownership stakes in cosmetics company Carol's Daughter, the Brooklyn Nets and a joint project with battery maker Duracell.
"The reality of it is, you want to do something that you own," said Timbaland, who ranks at number 20 on the list with $6m (£4m). "You want to own what you put your heart into. That's how you make money."
Snoop Dogg is at 14 with earnings of $8.5m (£5.3m), followed by 50 Cent at 15 with $7.5m (£4.7m).
Hip-hop's top 10 earners in full:
1. Dr Dre - $110 million
2. Diddy - $45 million
3. Jay-Z - $38 million
4. Kanye West - $35 million
5. Lil Wayne - $27 million
6. Drake - $20.5 million
7. Birdman - $20 million
8. Nicki Minaj - $15.5 million
9. Eminem - $15 million
10. Ludacris - $12 million
Watch Dr Dre's video for 'I Need a Doctor' below: