The 'Californication' group are to ring in 2013 with an intimate gig at the popular venue Chelsea, according to MTV News.
Anthony Kiedis and his bandmates are scheduled to take the stage at 11pm PT and will only pause the show briefly to celebrate the clock striking midnight.
Tickets for the event go on sale on Friday, September 7 at a price of $150 per seat.
Red Hot Chili Peppers recently unveiled two new singles 'Magpie's on Fire' and 'Victorian Machinery', with another pair to be released in October.
They also performed at the Lollapalooza Festival in Chicago in early August, despite thunderstorms hitting the area.
Watch Red Hot Chili Peppers perform 'Under the Bridge' at Lollapalooza 2012 below: