The rapper named the former *NSYNC star as his dream collaboration along with British jazz singer Sade.
"I would love to do a collaboration with Justin Timberlake, and [Noah '40' Shebib] he produced with Sade, and I would love to do a song with Sade," he told MTV.
Drake is currently working on an album of post-humous Aaliyah tracks and previously indicated that the new material will be out in 2012.
"To get 13, 14 new Aaliyah songs, everybody should be excited. It's not about me. It's not about 40. It's about her and her fans and us just getting the opportunity to give you something that we feel is great," he said.
Meanwhile, Timberlake is expected to make a return to music in the near future after recording new tracks with Timbaland and his production team.
Listen to Aaliyah's new single 'Enough Said' featuring Drake below: