Calvin Harris, Florence Welch debut 'Sweet Nothing' music video - watch
The pair have teamed up for 'Sweet Nothing', which will feature on the Scottish DJ's forthcoming album 18 Months.
The accompanying music video sees Welch walk out on to a stage in a working men's club dressed in a black suit.
Other scenes in the Vincent Haycock-directed clip see Harris pay an East London gang to attack Welch's abusive boyfriend on the streets of Dalston.
'Sweet Nothing' will be available to download in the UK on October 14, while 18 Months follows on October 29.
Harris's new album will feature further collaborations with Rihanna, Ellie Goulding, Tinie Tempah, Kelis and Dizzee Rascal.