The clip for the Korean rapper's latest track, which premiered on July 15, has been 'liked' 2,234,180 times at the time of writing.
The figure easily beats his nearest competitors LMFAO, whose 'Party Rock Anthem' has accumulated 1,574,963 likes, Justin Bieber's 'Baby' on 1,327,147 and Adele's 'Rolling in the Deep' with 1,245,641.
Guinness World Records Community Manager Dan Barrett said: "Having been the 'have you seen this?!' video of the last two months across the web, it's great to be able to award a record for this tremendously popular video.
"In years past it was unthinkable that something would be viewed a hundred million times, and now 'Gangnam Style' has achieved more than twice this figure in just three months on YouTube.
"Psy - your certificate is waiting here at our office, come pick it up any time!"
'Gangnam Style' is the singer's most successful single to date after topping the iTunes chart in the US and UK this week.
> Read Digital Spy's review of 'Gangnam Style'
Watch the official music video below: