The duo will release 'I Want You Back' on November 12 as the second cut from their recent album Contact, which was released earlier this year.
The single's release coincides with their headline tour of the UK, which includes a gig at London's KOKO on November 13.
Singer Shingai Shoniwa recently told Digital Spy that they did not expect the success of their previous album.
"I don't think the success of our last album was a fluke, but I definitely wasn't expecting it," she explained.
"I was expecting to just enjoy the ride and get some recognition of our contribution to the bandscape. It was nice to get that, so it would be a bit ungrateful to say, 'I won't accept anything less than that'."
Listen to Noisettes' new single 'I Want You Back' below: