The band will release their sixth studio album Opposites in the UK on January 28 and the collection will feature two discs' worth of material.
The accompanying artwork features a tree bent at a 90 degree angle, while glass bones hang from its branches.
The collection will come in two parts titled 'The Sand at the Core of Our Bones' and 'The Land at the End of Our Toes'.
It will be available as a CD/DVD and digital download, while a limited-edition box set will also be released.
Opposites will contain 20 tracks in total, with ten appearing on each disc.
Watch the video for Biffy Clyro's new track 'Stingin' Belle' below: