They will be joined by Chipmunk, Sway, Rudimental and Mystery Jets on the jaunt, which plays four dates in October and November across the UK.
The gigs, which will be held in Glasgow, Liverpool, Birmingham and London, will be staged entirely by young volunteers ages between 13 and 25 as part of O2's Think Big project.
All the acts performing will be supported by O2's Think Big Band, a group of ten young musicians who have been brought together by Radio 1 DJ Huw Stephens.
Tickets, which are priced at a £5 charitable donation, are on sale now.
The dates for this year's O2 Think Big tour appear in full below:
- October 29 - Glasgow, O2 ABC
- November 2 - Liverpool, O2 Academy
- November 4 - Birmingham, O2 Academy
- November 7 - London, InigO2
Watch a trailer for the 'Think Big' tour below: