The group were scheduled to play a number of arena dates across the UK for one last time next spring, but have had to cancel the shows after Bernie Nolan announced she has cancer.
"Due to very unforeseen circumstances The Nolans Farewell Tour has had to be cancelled," a statement from the promoter Kennedy Street reads.
"Ticket purchasers are requested to go back to their point of purchase for a refund."
Bernie Nolan has been diagnosed with cancer for a second time after being declared cancer-free back in December 2010.
The singer has explained that this time the disease is incurable, but it is treatable and can be contained.
She added that she is determined to fight the cancer, saying: "I refuse to sit around like I've got a death sentence hanging over my head. I'm going to fight this for ever. It can get stuffed."