The singer will join a lineup including Bruno Mars, One Direction and Little Mix at the event, which takes place at London's O2 Arena on December 8.
Rizzle Kicks, Lawson, JLS and The Script will also play the Saturday concert of the event.
However, tickets for the December 8 day of the Jingle Bell Ball sold out in under an hour when they went on sale this morning (November 5).
Acts for the December 9 show of the Jingle Bell Ball 2012 are due to be announced in the coming weeks.
Cheryl Cole was the surprise guest at the Capital FM Summertime Ball at Wembley Stadium back in June.
Watch the music video for Cheryl Cole's 'Call My Name' below: