The New York duo will release their first studio set in May 2013 and will precede the collection with their new single 'Fantasy' in March.
The track serves as the follow-up to their previous cuts 'Hurricane', 'Bones' and 'Dark Doo Wop'.
MS MR have gained a following over the past year, with fans including Jay-Z, Tom Ford and Radio 1 DJ Nick Grimshaw.
The band will play two headline shows in the UK later this year, stopping off at Manchester's Soup Kitchen on November 28 and London's Electrowerkz on November 29.
Watch the music video for MS MR's 'Dark Doo Wop' below: