The promo for their as-yet unamed next single from their latest album Battle Born was shot inside Blackpool's iconic Tower Ballroom, and features Edward Scissorhands star Winona Ryder.
The Blackpool Gazette reports that the band met and posed for pictures with fans the night before the video shoot, after watching Skyfall at the Blackpool Odeon.
Cinema manager Samantha Sinclair said: "It was really exciting. They were happy to have photos taken with locals... They were really nice, not very chatty but I know they had to cancel their gig on Tuesday because Brandon lost his voice."
The band returned to the north after cancelling their recent Manchester date after four songs, due to singer Brandon Flowers's throat problems.
Flowers was recently asked in an interview: "You live in Vegas. It seems quite brash: all sex and gambling. A bit like Blackpool," to which Flowers responded: "I've been to Blackpool. It's not like Blackpool."
Watch the video for The Killers' 'Miss Atomic Bomb' below: