The musician - real name Abel Tesfaye - has opened a ballot for tickets to the performance at a mystery West London location, to be held on Sunday November 25.
Fans can apply at www.theweeknd.co.uk or www.islandrecords.co.uk/theweeknd/.
The gig is in support of The Weeknd's new release Trilogy, which collects remixed and remastered versions of the three mixtapes House of Balloons, Thursday and Echoes of Silence.
It also features three brand new tracks - 'Twenty Eight', 'Valerie' and 'Till Dawn (Here Comes the Sun)'.
Winners will be contacted before 9pm tonight (November 23). Attendees must be 18+ years old.
Watch the video for 'Wicked Games' below: