The latest edition of the popular compilation series sold 295,000 copies in its first week, the BBC reports.
The sales would see it take this week's number one, but multi-artist compilation albums do not qualify for the main album chart in the UK.
The figures are almost double of those achieved by Mumford and Sons' Babel. Their album sold 158,000 copies in its first week of release in September. Babel is currently the fastest-selling album by a single artist in 2012.
The previous edition of the compilation series Now That's What I Call Music! 82 has sold over 700,000 copies since it was released in July.
The latest edition features number one singles from Robbie Williams, Psy and Calvin Harris, as well as tracks from JLS, Rita Ora and Amelia Lily.
Rihanna's seventh studio album Unapologetic entered at the top spot in this week's album chart, giving her her fourth UK number one album.
However Unapologetic sold just under 100,000 copies, around one-third of the compilation album's sales.
It was reported in September that the Now That's What I Call Music! series may be forced to end, due to the takeover of EMI by Universal.