The DJ - real name Joel Zimmerman - made the claim during a conference in San Francisco and insisted that the industry centres around the model of "minimal work for maximum profit".
"Burn all electronic music down, I don't care," Deadmau5 is quoted by Mixmag as saying. "At the end of the day, scenes don't evolve. Scenes are scenes. They're there and then they're not.
"The way I see EDM right now, it's a healthy industry for sure. Minimal work for maximum profit, right?"
He then insisted that traditional DJing is "no longer a technical feat" as producers have become more like artists over the past few years.
"Today it's more artist driven, more about the producer as opposed to the guy who can string some tunes together," he added. "It's no longer a technological feat to string some tunes together."
Watch the music video for Deadmau5 and Gerard Way's 'Professional Griefers' below: