The band took to the stage at New York's Madison Square Gardens alongside Sir Paul McCartney, Coldplay's Chris Martin, Kanye West, Bruce Springsteen and Jon Bon Jovi in what was billed by producers as "the greatest lineup of legends ever assembled on stage".
The Who, Alicia Keys and Eddie Vedder were also among those on the bill, while McCartney joined forces with the surviving members of Nirvana to play together live for the first time in almost 20 years.
They also unveiled a brand new song together, titled 'Cut Me Some Slack'.
An album of 24 songs from the show, called 12-12-12, is available to download now via Columbia Records.
Proceeds from the concert and sales of the album will benefit the Robin Hood Foundation's Relief Fund, a charitable organisation which helps those in poverty in the New York area.
Click through our gallery of the 12-12-12 Concert for Sandy Relief below: