The garage and hip-hop group, best known for their 2001 hit '21 Seconds', will play London's IndigO2 on March 21.
Original members Romeo, MC Harvey, Lisa Maffia, Oxide & Neutrino, Megaman and Asher D will all perform at the gig.
So Solid Crew have continued to work on music with various lineups since their breakthrough, while some members focused on TV work.
Romeo and MC Harvey have both recently appeared on Celebrity Big Brother, while Maffia won ITV2's short-lived reality series CelebAir. All three took part in separate series of Channel 4's The Games.
Tickets for their comeback gig go on sale on Friday, January 18 at 9am.
Watch So Solid Crew's video for '21 seconds' below: