50 Cent teams up with Snoop Dogg in new music video
The rapper performs the track alongside guest features Snoop Dogg and Young Jeezy in the clip, which premiered on Vevo.
The song follows his recent Eminem-assisted single 'My Life', which entered at number two in the UK charts and 27 in the US earlier this month.
'Major Distribution' marks the latest release from the star's long-delayed forthcoming album Street King Immortal, which is out this spring.
The LP's new release date coincides with the tenth anniversary of his debut album Get Rich Or Die Tryin', which sold over 15 million copies worldwide.
50 Cent recently insisted that he only accepts criticism from Eminem, adding: "I can't accept constructive criticism from someone if I'm not sure what their intentions are."