Streisand is to be presented a lifetime achievement award by her friend and former US President Bill Clinton in New York City on April 22.
Minnelli and Chenoweth will be paying tribute to Streisand's musical legacy alongside crooner Tony Bennett and trumpeter Wynton Marsalis.
Pierce Brosnan, Blythe Danner, Richard Dreyfuss and Kris Kristofferson are also expected to honour Streisand during the gala.
This event is being put together by the Film Society of Lincoln Centre.
Streisand has won numerous prestigious awards throughout her career, including two Oscars, eight Grammys and five Emmy Awards.
Watch Barbra Streisand and Barry Gibb perform 'Guilty' below: