Kiesza is on course to claim her first UK number one single with 'Hideaway', which has sold over 86,000 copies at this midweek stage.
Sigma slip to number two with 'Nobody to Love', while Shift K3y is at three with 'Touch'.
John Legend's 'All of Me' stays firm at four and Aloe Blacc's 'The Man' slides to five.
Meridian Dan is at six with 'German Whip', while Elyar Fox is at seven with 'A Billion Girls'.
Further down, Showtek and Justin Prime are new at 27 with their latest cut 'Cannonball (Earthquake)'.
Over on the album chart, Paolo Nutini is on course to claim his second British chart-topper with new collection Caustic Love.
The Scottish star has sold over 59,000 copies already this week and is looking likely to have the fastest-selling album of 2014 so far.
The Vamps follow at two with their debut set Meet The Vamps, while Paloma Faith's A Perfect Contradiction completes the Top 3.
John Legend is at four with Love in the Future and Kaiser Chiefs slip to five with their former chart-topper Education, Education, Education & War.
Jethro Tull's Ian Anderson is at six with new concept album Homo Erraticus, while former X Factor finalist Rhydian is at 15 with new collection One Day Like This.
Watch the music video for Kiesza's 'Hideaway' below: