The former Sex Pistols frontman told the Daily Star that he "despises" drugs after seeing the effects it had on former band member Sid Vicious.
Punk rocker Lydon, said: "If only Sid had been able to grow out of the drug thing. He went into it like such a child. He did it in such a goofy, innocent way."
"For him it was a fantastically decadent world that he assumed carried applause with. And he was horribly rewarded because people would think he was special as he was so off his tree."
The I'm a Celebrity...Get Me Out of Here! star added: "But deep down, poor old Sid knew he was not special. That's what we are as human beings, full of self-doubt and fear - and that's no bad thing. Heroin was a symbol of deeper pain for him."