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The brother-sister duo, who failed to break the Top 20 with their debut album Pop, will hit the road with Leon Jackson instead, reports The Sun.
"We have had to make some changes to our tour, and we want you to be the first to know all about it!" they said in a statement.
"We're joining forces with our friend Leon Jackson to put on an even more fun packed show! Woo hoo!
"We think this will be better value for money, so tell all of your friends and family who don't have a ticket yet to come and join the party with us! It's gonna be brilliant!"
Jackson recently announced plans to tour the UK in May and June.
Same Difference finished third in the fourth series of The X Factor in 2007.
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